2-BroMo-1-(2-pyrazinyl) Ethanone - Names and Identifiers
2-BroMo-1-(2-pyrazinyl) Ethanone - Physico-chemical Properties
Molecular Formula | C6H5BrN2O
|
Molar Mass | 201.02 |
Density | 1.666±0.06 g/cm3(Predicted) |
Boling Point | 269.0±25.0 °C(Predicted) |
Flash Point | 116.461°C |
Vapor Presure | 0.007mmHg at 25°C |
pKa | -0.91±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.581 |
2-BroMo-1-(2-pyrazinyl) Ethanone - Introduction
2-Bromo-1-(2-pyrazinyl) ethanone, chemical formula C8H7BrN2O, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Bromo-1-(2-pyrazinyl) ethanone is white crystal or crystalline powder.
-Solubility: It dissolves in organic solvents such as ethanol, chloroform and dimethylformamide, but has poor solubility in water.
-Melting point: Its melting point is about 86-88°C.
-Molecular weight: Its molecular weight is 218.06g/mol.
Use:
-2-Bromo-1-(2-pyrazinyl) ethanone is commonly used as a pharmaceutical and pesticide intermediate. It is involved in the synthesis of various bioactive compounds, such as pyrazine drugs, coumeterone alkalophilic substances.
Preparation Method:
-2-Bromo-1-(2-pyrazinyl) ethanone can be prepared by the following methods:
1. The pyrazine is reacted with alkali metal bromide (such as potassium bromide, sodium bromide, etc.).
2. Acidify 2-pyrazinamine with acetic acid, and then react the resulting amide with acetone bromide.
Safety Information:
-2-Bromo-1-(2-pyrazinyl) ethanone is relatively safe under correct use and storage.
-It may be irritating to the skin, eyes and respiratory system, so wear protective gloves, goggles and a mask when using it.
-Avoid inhaling its powder and avoid contact with skin and eyes.
-It is recommended to use in a well-ventilated place.
-Observe relevant chemical safety practices during handling and disposal.
Last Update:2024-04-09 20:49:11